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AC IMMUNE SA

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$2.86 0.0289(2.89%) ACIU at 04 Dec 2025 04:25 PM Biotechnology
Lowest Today 2.75
Highest Today 2.85
Today’s Open 2.8
Prev. Close 2.77
52 Week High 4.00
52 Week Low 1.43
Day’s Range: Low 2.75 High 2.85
52-Week Range: Low 1.43 High 4.00
1 day return -
1 Week return -5.66
1 month return -14.24
3 month return +31.32
6 month return +70.48
1 year return -11.56
3 year return +16.94
5 year return -44.67
10 year return -

Institutional Holdings

Bvf Inc 19.70

Wells Fargo & Co 1.02

Renaissance Technologies Corp 0.82

BlackRock Inc 0.41

Northern Trust Corp 0.38

iShares Biotechnology ETF 0.37

Millennium Management LLC 0.29

Deutsche Bank AG 0.25

DWS ESG Biotech LC 0.25

Dimensional Fund Advisors, Inc. 0.20

Citadel Advisors Llc 0.15

Marshall Wace Asset Management Ltd 0.14

Monega ARIAD Innovation R 0.13

Handelsbanken Fonder AB 0.10

Eversept Partners, LLC 0.10

Morgan Stanley - Brokerage Accounts 0.07

Fidelity Nasdaq Composite Index 0.06

Geode Capital Management, LLC 0.06

BlackRock Health Sciences 0.06

iShares Nasdaq US Biotech ETF USD Acc 0.05

Two Sigma Investments LLC 0.03

DFA US Targeted Value I 0.03

Two Sigma Advisers, LLC 0.03

Top Class Healthcare FI 0.03

SEI Investments Co 0.02

China Universal Asset Mgmt Co.Ltd 0.02

China Universal NASDAQ Bio-Tch ETF(QDII) 0.02

Banque Cantonale Vaudoise 0.02

Acadian All Ctry Wld ex US SCap Eq CL A 0.02

DFA US Vector Equity I 0.02

Dimensional US Targeted Value ETF 0.02

DFA US Small Cap I 0.01

Squarepoint Ops LLC 0.01

Dimensional Global Small Coms USD Acc 0.01

Dimensional World Equity GBP Acc 0.01

SEI International Equity F (SIT) 0.01

DFA US Micro Cap I 0.01

Voya Multi-Manager International Sm Cp A 0.01

Dimensional VA US Targeted Value 0.01

Handelsbanken Europa Småbolag (A1 SEK) 0.01

Market Status

Strong Buy: 3

Buy: 1

Hold: 0

Sell: 0

Strong Sell: 0

Fundamentals

Market Cap 278.66 M

PB Ratio 3.871

PE Ratio 0.0

Enterprise Value 171.80 M

Total Assets 230.91 M

Volume 279662

Company Financials

Annual Revenue FY23:1000 0.0M, FY22:3935000 3.9M, FY21:0 0.0M, FY20:15431000 15.4M, FY19:111026000 111.0M

Annual Profit FY23:null 0.0M, FY22:3935000 3.9M, FY21:null 0.0M, FY20:15431000 15.4M, FY19:111026000 111.0M

Annual Net worth FY23:-68238000 -68.2M, FY22:-70753000 -70.8M, FY21:-72996000 -73.0M, FY20:-62105000 -62.1M, FY19:45442000 45.4M

Quarterly Revenue Q3/2025:939000 0.9M, Q2/2025:1306000 1.3M, Q1/2025:990000 1.0M, Q3/2024:25485000 25.5M, Q2/2024:687000 0.7M

Quarterly Profit Q3/2025:939000 0.9M, Q2/2025:1306000 1.3M, Q1/2025:990000 1.0M, Q3/2024:25485000 25.5M, Q2/2024:null 0.0M

Quarterly Net worth Q3/2025:-15858000 -15.9M, Q2/2025:-21189000 -21.2M, Q1/2025:-19029000 -19.0M, Q3/2024:5503000 5.5M, Q2/2024:-22760000 -22.8M

Fund house & investment objective

Company Information AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative disease. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

Organisation Biotechnology

Employees 133

Industry Biotechnology

CEO Dr. Andrea Pfeifer Ph.D.

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