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Alnylam Pharmaceuticals, Inc.

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$470.2 0.018(1.8%) ALNY at 04 Dec 2025 04:25 PM Biotechnology
Lowest Today 460.41
Highest Today 479.56
Today’s Open 466.485
Prev. Close 464.93
52 Week High 495.55
52 Week Low 205.87
Day’s Range: Low 460.41 High 479.56
52-Week Range: Low 205.87 High 495.55
1 day return -
1 Week return +4.89
1 month return +11.83
3 month return +4.45
6 month return +55.14
1 year return +85.88
3 year return +109.15
5 year return +265.59
10 year return -

Institutional Holdings

Capital World Investors 12.82

FMR Inc 12.06

Vanguard Group Inc 10.14

American Funds Growth Fund of Amer A 7.77

Capital Group Growth Fnd of Amer Comp 7.77

BlackRock Inc 7.29

Capital Research Global Investors 5.49

Regeneron Pharmaceuticals Inc 3.39

T. Rowe Price Investment Management,Inc. 3.27

Vanguard Total Stock Mkt Idx Inv 3.13

State Street Corp 2.57

Dodge & Cox 2.44

T. Rowe Price Associates, Inc. 2.40

Baillie Gifford & Co Limited. 2.31

American Funds New Perspective A 2.23

Capital Group New Perspective Comp 2.23

Vanguard Mid Cap Index Institutional 2.22

American Funds AMCAP A 1.83

Capital Group AMCAP Composite 1.83

Geode Capital Management, LLC 1.77

JPMorgan Chase & Co 1.69

Orbis Allan Gray Ltd 1.62

Wellington Management Company LLP 1.58

Dodge & Cox Stock I 1.55

NORGES BANK 1.55

Fidelity Growth Compy Commingled Pl S 1.43

American Century Companies Inc 1.37

American Funds IS® Growth 1 1.29

Capital Group Growth Composite 1.29

American Funds Fundamental Invs A 1.22

Capital Group Fundamental Invtrs Comp 1.22

Vanguard Health Care Inv 1.22

T. Rowe Price Mid-Cap Growth 1.22

T. Rowe Price US Mid-Cap Growth Equity 1.22

Groupama Asset Management 1.18

American Funds New Economy A 1.17

Capital Group New Economy Comp 1.17

Vanguard Growth Index Investor 1.14

Winslow Capital Management, LLC 0.90

Bank of America Corp 0.81

Market Status

Strong Buy: 12

Buy: 12

Hold: 7

Sell: 1

Strong Sell: 1

Fundamentals

Market Cap 61423.68 M

PB Ratio 256.7559

PE Ratio 1408.8787

Enterprise Value 58637.49 M

Total Assets 4239.98 M

Volume 1092993

Company Financials

Annual Revenue FY24:2248243000 2248.2M, FY23:1723609000 1723.6M, FY22:1037418000 1037.4M, FY21:844287000 844.3M, FY20:492853000 492.9M

Annual Profit FY24:1924873000 1924.9M, FY23:1447795000 1447.8M, FY22:868601000 868.6M, FY21:704143000 704.1M, FY20:414801000 414.8M

Annual Net worth FY24:-278157000 -278.2M, FY23:-509865000 -509.9M, FY22:-1131156000 -1131.2M, FY21:-852824000 -852.8M, FY20:-858281000 -858.3M

Quarterly Revenue Q3/2025:1249026000 1249.0M, Q2/2025:773689000 773.7M, Q1/2025:594189000 594.2M, Q4/2024:593166000 593.2M, Q3/2024:500919000 500.9M

Quarterly Profit Q3/2025:1051795000 1051.8M, Q2/2025:630736000 630.7M, Q1/2025:523148000 523.1M, Q4/2024:490349000 490.3M, Q3/2024:415014000 415.0M

Quarterly Net worth Q3/2025:251084000 251.1M, Q2/2025:-66277000 -66.3M, Q1/2025:-57479000 -57.5M, Q4/2024:-83763000 -83.8M, Q3/2024:-111570000 -111.6M

Fund house & investment objective

Company Information Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference. It offers ONPATTRO and AMVUTTRA for hereditary transthyretin-mediated amyloidosis; GIVLAARI for acute hepatic porphyria; OXLUMO for primary hyperoxaluria type 1; and Leqvio for hypercholesterolemia. It also develops vutrisiran, which is in phase III clinical trial for transthyretin amyloidosis (ATTR) with cardiomyopathy; Nucresiran that is in phase I clinical trial for ATTR amyloidosis; Fitusiran, which is in phase III clinical trial for hemophilia; cemdisiran that is in phase III clinical trial for Myasthenia Gravis and paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and ALN-6400, which is in phase I clinical trial for bleeding disorders. In addition, the company is also developing Zilebesiran, which is in phase II clinical trial for hypertension; Rapirosiran that is in phase II clinical trial for Metabolic dysfunction-associated steatohepatitis; ALN-4324, which is in phase I clinical trial for type 2 diabetes mellitus; ALN-PNP that is in phase I clinical trial for non-alcoholic fatty liver disease; ALN-APOC3, which is in phase I clinical trial for dyslipidemia; Mivelsiran that is in phase II clinical trial for cerebral amyloid angiopathy, and phase I clinical trial for Alzheimer's disease; and ALN-HTT02 that is in phase I clinical trial for Huntington's disease. Further, it develops ALN-SOD, which is in phase II clinical trial for SOD1 Amyotrophic lateral sclerosis; Elebsiran that is in phase II clinical trial for Hepatitis B and D virus infections; ALN-BCAT that is in phase I clinical trial for hepatocellular carcinoma; and ALN-ANG3. It has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Regeneron Pharmaceuticals, Inc.; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Organisation Biotechnology

Employees 2230

Industry Biotechnology

CEO Dr. Yvonne L. Greenstreet M.B.A., M.D.

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