Karyopharm Therapeutics Inc Share Price Today: Live Updates & Key Insights

Karyopharm Therapeutics Inc share price today is $7.6857, up -1.29%. The stock opened at $7.79 against the previous close of $7.73, with an intraday high of $9.01 and low of $7.435.

Karyopharm Therapeutics Inc Share Price Chart

Karyopharm Therapeutics Inc

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Karyopharm Therapeutics Inc Share Price Performance

$7.6857 -0.0129(-1.29%) KPTI at 23 Mar 2026 01:53 PM Biotechnology
Lowest Today 7.435
Highest Today 9.01
Today’s Open 7.79
Prev. Close 7.73
52 Week High 10.99
52 Week Low 3.51
Day’s Range: Low 7.435 High 9.01
52-Week Range: Low 3.51 High 10.99
1 day return -
1 Week return -11.21
1 month return -24.45
3 month return +3.54
6 month return +29.91
1 year return +17.64
3 year return +135.29
5 year return -35.59
10 year return -

Karyopharm Therapeutics Inc Institutional Holdings

Opaleye Management Inc 5.07

Affinity Asset Advisors, LLC 4.85

T. Rowe Price Small-Cap Value 4.68

T. Rowe Price Investment Management,Inc. 3.82

T. Rowe Price U.S. SC Value Eq Tr-D 3.19

Vanguard Group Inc 3.05

Vanguard Total Stock Mkt Idx Inv 2.78

Adage Capital Partners Gp LLC 2.30

Davidson Kempner Capital Management LP 1.69

BRAIDWELL LP 1.65

Exome Asset Management LLC 1.61

Boxer Capital Management, LLC 1.38

BlackRock Inc 1.26

Vanguard Institutional Extnd Mkt Idx Tr 1.06

Geode Capital Management, LLC 1.02

Two Sigma Investments LLC 0.81

Susquehanna International Group, LLP 0.81

BOOTHBAY FUND MANAGEMENT, LLC 0.79

Catalio Capital Management, LP 0.78

Avidity Partners Management LP 0.73

Marshall Wace Asset Management Ltd 0.70

Group One Trading, LP 0.56

CAM Group Holding A/S 0.55

C WorldWide Healthcare Select 1A 0.55

Walleye Trading Advisors, LLC 0.52

Fidelity Extended Market Index 0.49

Blackrock Extended Mkt Fund CF 0.30

Bridgeway Ultra-Small Company 0.27

Extended Equity Market Fund K 0.26

iShares Micro-Cap ETF 0.22

T. Rowe Price U.S. Equities Tr 0.21

Nomura Healthcare Fund Class I 0.18

Fidelity Total Market Index 0.16

Spartan Extended Market Index Pool F 0.15

Fidelity Series Total Market Index 0.13

NT Ext Equity Mkt Idx Fd - L 0.11

Bridgeway Ultra-Small Company Market 0.09

Spartan Total Market Index Pool G 0.07

Vanguard Instl Ttl Stck Mkt Idx Tr 0.07

T. Rowe Price Extended Equity Market Idx 0.06

Karyopharm Therapeutics Inc Market Status

Strong Buy: 2

Buy: 3

Hold: 1

Sell: 0

Strong Sell: 0

Karyopharm Therapeutics Inc Fundamentals

Market Cap 139.96 M

PB Ratio 12.0484

PE Ratio 0.0

Enterprise Value 309.83 M

Total Assets 108.42 M

Volume 1496158

Karyopharm Therapeutics Inc Company Financials

Annual Revenue FY25:146067000 146.1M, FY24:145237000 145.2M, FY23:145866000 145.9M, FY22:157074000 157.1M, FY21:209819000 209.8M

Annual Profit FY25:140118000 140.1M, FY24:139230000 139.2M, FY23:140542000 140.5M, FY22:151861000 151.9M, FY21:206417000 206.4M

Annual Net worth FY25:-196039000 -196.0M, FY24:-76422000 -76.4M, FY23:-139768000 -139.8M, FY22:-165291000 -165.3M, FY21:-124088000 -124.1M

Quarterly Revenue Q4/2025:34079000 34.1M, Q3/2025:44044000 44.0M, Q2/2025:37929000 37.9M, Q1/2025:30015000 30.0M, Q4/2024:30542000 30.5M

Quarterly Profit Q4/2025:32595000 32.6M, Q3/2025:41931000 41.9M, Q2/2025:36878000 36.9M, Q1/2025:28714000 28.7M, Q4/2024:29211000 29.2M

Quarterly Net worth Q4/2025:-102198000 -102.2M, Q3/2025:-33127000 -33.1M, Q2/2025:-37252000 -37.3M, Q1/2025:-23462000 -23.5M, Q4/2024:-30780000 -30.8M

About Karyopharm Therapeutics Inc & investment objective

Company Information Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compounds include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also develops Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating other myeloproliferative neoplasms and TP53 wild-type solid tumors. In addition, the company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, the company has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed or refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Organisation Biotechnology

Employees 228

Industry Biotechnology

CEO Mr. Richard A. Paulson M.B.A.

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Karyopharm Therapeutics Inc FAQs

What is the share price of Karyopharm Therapeutics Inc today?

The current share price of Karyopharm Therapeutics Inc is $7.6857.

Can I buy Karyopharm Therapeutics Inc shares in India?

Yes, Indian investors can buy Karyopharm Therapeutics Inc shares by opening an international trading and demat account with Motilal Oswal.

How to buy Karyopharm Therapeutics Inc shares in India?

You can easily invest in Karyopharm Therapeutics Inc shares from India by:

Can I buy fractional shares of Karyopharm Therapeutics Inc?

Yes, many platforms allow you to buy fractional shares starting from as low as $1.

What is the market capitalization value of Karyopharm Therapeutics Inc?

Karyopharm Therapeutics Inc has a market cap of $139.96 M.

In which sector does Karyopharm Therapeutics Inc belong?

Karyopharm Therapeutics Inc operates in the Biotechnology sector.

What documents are required to invest in Karyopharm Therapeutics Inc stocks?

To invest, you typically need:

What is the PE and PB ratio of Karyopharm Therapeutics Inc?

The PE ratio of Karyopharm Therapeutics Inc is N/A and the PB ratio is 12.05.